Biostability of a New Cardiovascular Material
نویسنده
چکیده
Introduction: Polyurethanes (PU) have long been used for biomedical applications due to their excellent mechanical properties and reasonable biocompatibility. However, polyether urethane elastomers are susceptible to biodegradation. Silicones are known to be biostable and biocompatible, making them an ideal replacement for the polyether soft segment of polyurethanes. As a result, a new silicone-polyurethane copolymer, Elast-Eon 2A, has been developed by AorTech Biomaterials in Australia. St. Jude Medical began marketing this material as Optim insulation in its pacemaker and defibrillator leads in 2006. This study compared the biostability of Elast-Eon2A material to Pellethane 2363-55D (55D) which is clinically acceptable, industry standard polyurethane using both an accelerated in vitro metal ion oxidation (MIO) and in vivo environmental stress cracking (ESC) methods. Surface degradation was investigated using Optical microscope, SEM, and ATR-FTIR spectroscopy.
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